Tagged medical

Run trial subgroup and heterogeneous treatment effect analyses with interaction tests

Run trial time-to-event analysis with Cox models, RMST and competing risks

Write clinical trial statistical reports with Table 1, analysis sets and estimands

Classify variant pathogenicity with the ACMG AMP framework and calibrated evidence

Look up ClinVar pathogenicity calls and resolve conflicting interpretations

Resolve dbSNP rsIDs, merge histories and variant notation like HGVS and VCF

Query gnomAD allele frequencies, constraint scores and rare variant filters

Call HLA alleles from sequencing data for transplant and neoantigen work

Call microsatellite instability from exome, genome and panel data

Annotate variant lists in batch from ClinVar, gnomAD, dbNSFP and CADD

Call star alleles and drug-gene phenotypes for pharmacogenomic reports

Build and validate polygenic risk scores with ancestry-aware reference panels

Assign COSMIC mutational signatures to tumor genomes to infer DNA damage causes

Calculate tumor mutational burden with assay-specific calibration and filters

Rank rare-disease variants from family sequencing with phasing and phenotype scores

Compare cell-type composition across IMC cohorts with patient-level statistics

Build and validate clinical time-to-event models with penalized Cox and survival forests

Stratify patients into multi-omics subtypes with similarity network fusion

Detect aberrant splicing in rare-disease patients against a control panel

Classify variant pathogenicity with ACMG AMP germline and somatic tier guidance

Run clinical trial analysis from SDTM and ADaM data to CONSORT-ready reporting

Run imaging mass cytometry from raw MCD files to spatial patient analysis

Find clinical trials for a gene, variant or condition from ClinicalTrials.gov

Screen genotypes against disease gene panels and rank carried variants by significance

Classify germline variants with ACMG/AMP criteria and write clinical-grade reports

Generate English clinical PDF reports from whole exome sequencing data

Generate Spanish clinical PDF reports from whole exome sequencing data

Run survival analysis, Cox regression and diagnostic test evaluation for clinical data

Plan trial sample size, randomization, endpoints and CONSORT reporting for RCTs

Search ClinicalTrials.gov in plain language for trials, enrollment and results

Look up variant clinical significance in NCBI ClinVar and annotate VCF files

Answer medical questions from structured biomedical knowledge bases and datasets